SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f853053eb8f0cf4b97d55369320281199fc3fa554a95bb75793dcac113ce523' 
  AND token = 'R7I4i504gFOjgwebyQAE3Hgm3vqRiymXh0JQyvRJISQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}