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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e418f93d632769312d071efa42516adb0ced480053aa9a0dad86b3ada0589a0d' 
  AND token = 'NHSBBwP9fsZdHw3bKhEENaGQXuYPqb6rTxKRquXmTME=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}