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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b389f8740ce648b5511fc0fa01b5070fde020215ebb05eafcb381f46c09a7b06' 
  AND token = 'UbPFCsy/gFLv0VvscHZygPoTDIuKJ8Wzo7KEaTWTQMU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}