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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48fb93fbc3dd3c04066417fc2118050b70303247a54ec3c575aead0bb2ac8921' 
  AND token = 'NJwpbNja/4YcStZWFRU8WZmbZxGCVa0UEYdXHp2mMY8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}