SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ddf820c39c868c88978d7077fc808cf7c192e575d3b8a41172784bd676b47fc5' 
  AND token = 'LsCXN9OlMMR2UZvbcRwWz8bXyjjQdEWRa6ZnVjlIMOE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}