SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '69e22bd0ec702642bc5a6f231f08d170dcc3673532cfc8e5e83ea6347c98ff5d' 
  AND token = 'wle+Z5buNzwL1v/ItKR2MzgFC/Mr6oRuFExh1D3QRWw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}