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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ea4f24f1f831b91f8cabc976e13524294835fdf9edfa3b93c9d766b10b093bc' 
  AND token = '+C7dQ3c2KGHbfqDl9oCgW+4CoMfSRcsHFpm4nJNHeng=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}