SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66e14a16675dd1842beeec274f0e7a370e227468017470ce972fa65eb4ece2c2' 
  AND token = 'MwcBV3otD8vFgEkGVy5lw/mvR2puH8E/IvoR+OyTss0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}