SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1480646a8bb00cc18c85537eb1155ba95690659592f1c823a2e32b8fbd494ff' 
  AND token = 'jC49kx1Y1X9Hc0MyttQ6eF60aVzSyL5CNnAJqgal5ss=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}