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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ffc4061fd99aebe0714917758594ec260ab1064aa67298c0875f8572ab4c1e6a' 
  AND token = 'PrPzyA3PAFyK5ZaQWo3t1jXBgu/52luoCTuzPiQzggM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}