SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '01d253b8146cfae55a564203541c4cd29bd2c138855f7335db61f1b977ac2604' 
  AND token = 'H50CD9d932ZHjjHGzXNrINjxLqELQLn1xvTMT7i/Vik=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}