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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3bbcfcd1a4d315e1726f8aa62bb9f1ea2b207aee43016702483d190fdb359566' 
  AND token = 'zCgsPY4hQ2ShVt6ZE1FBJDGq+2iEeEG41r8bE9W0CFE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}