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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7211d3e81ec1cd652e585423df001bc2611ae71ece476985529930d2c9a354e6' 
  AND token = '6do1BvltBshRPECCoufKfRijbM6nsU8Yv+daKcTsuwI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}