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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b310a5c95b03af9574caf664eeff4210e28ff0271b146157f19820d7ba91189f' 
  AND token = 'o6EdkyRbTiKC/wVo8KnGtuRMEzrxTjWFrJlObvpeDFM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}