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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33f5825512bc85c77eb3881cac3e46b2336e8941e7d21d24121001555a308af0' 
  AND token = 'qOM7TverDuz2Xoty1Suuc/Ap4EDDRKzrYOwUtUdwqFc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}