SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2de8a796d5ceb6927f502e2d9453f6f527674b8a554a9f61c97a57a49ef78c20' 
  AND token = '+rx6/CX9OizxcPY5BNU7I3c354SC2/97AEK/dyEXD/U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}