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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '60da96c7b42cbcc2c8c4cd18a180a018673e3b196aad2904754cc3e3dd1a63f6' 
  AND token = 'G7Z+s9nlkjEg2QAqcYTku8yDxC+hhwp/jaxz9xNwkZI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}