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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1f100484aa69c19f78e0866a5008e32f896b77915841a5047cdf6e2b008ba2a8' 
  AND token = 'VSDaw04LWWzXQfxX+SmoFseArWMLzdH1CHU1yBXr8io=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}