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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd877d77cbb7145467da87c108b2d6d5022767a36846b47aff367ba17431a6131' 
  AND token = '444ZE14jOgRHCs8cZNp8P3x31J6RyydreiwrDdhAJUY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}