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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c16ac27d90e7d5740b3c1c2f4ac9f0d5c4fd0b950b178c0fd26cfefc863200a' 
  AND token = 'pZwrN5So4ogyljxvFF1E3okHcTzzMEjMWtVwjKV0NV8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}