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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10ec8644f98a2de546b1f726fdc7ec3970eccfdc1fb7c641e6cdaee1999a04b2' 
  AND token = 'xPo6dYW6fsVbE3hWGVvqmO260uQtWgV7ZHL1f45o6Ko=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}