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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c6ebed236a2254841112d812978c4f435fa7b991a86e59be47b9a79724b8e3d2' 
  AND token = 'oqRB8FLokadQL4F8y36J+3mozGKki3IV+FVdpOUHSeE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}