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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '274e6a36fb1ddaa37e3ecae87fc469ec9378438598a7df8c1a57b227e2eb43dd' 
  AND token = 'Gh9vky4+/Vj88+FY5h5zvFirW+8X6ckHAOleNg9srFY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}