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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3f838a80e1dcaa64e1504e29ca61653fdd8752049c6d9b516cddb62c98746e8a' 
  AND token = 'ZVc+J2P0d9aDwfCz7WYJhOR2fVvWzHSYpDMpcAFQrTc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}