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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dd614e5408970d56dc98cc1d0fa55a4ea66c1b5b848032a36905ce6d2e2c7788' 
  AND token = 'H5ru91xpOwC+QW9C+zL6yGvvUjiWdtBcXvHLRpOpG/E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}