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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72ecc9481eb63b76cd9d2878a31c8b6a4b996d0646ef51e48167aae0c175ad72' 
  AND token = 'sCTLWICMatZWFsOVqkCqMzSbVMt1wXWRZDyljYo8aLw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}