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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7db25ab204163456e976edd2d90f5e28a401f5f331262eb87e84507a052469f9' 
  AND token = 'NXi//JdZaZ0GLtqNvkAQ32Q9mY5E9uQT5OublW4Zl9k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}