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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '28f7fa76930815bfb3754612f1f1f5d0b55ffcb87fb6f23d429692a6d84f4778' 
  AND token = 'O11IfAntCDM/0IQCDSVIWsDCgCrAg4kLk7f6e282AdM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}