SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3ad62b26f2f68d043e3bd5f0f4c865bdea2034a1beded30de0ba29298515a374' 
  AND token = 'H+wMWYeBKQiip6Nk+2ZW29Ow/JS5KFcrwCihjDTSxwc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}