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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43cfb6d5577406e09fdbde7fe38ceb1660dae37417484fe279c0a34f8b3ea167' 
  AND token = 'PrXDmEHKoxhOJSnAhNlyCE2RKyU8KbyhYxIQ2IWG310=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}