SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6867e53e81c997bab2c7c61b8604e0d8cb46e37f77711712bde84d97a320a7a7' 
  AND token = 'qEY1E2ZzuE930XLQGBiofyeZG16vsPRCYHqtiqZ5nXo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}