SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33e1ac2ab8fd073734fd777653a3afa1e7fe4990017078642989c91f000eb356' 
  AND token = 'mPEHqu06jc19rEPGJEhOxXbm7Osaz3ZTEwW9tTBgon8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}