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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'efef9187a95d4bb67d8cc378593b450f86b493c87c3c1c0045cea1cfc1391bd2' 
  AND token = '+159LW7zZp6MXY2D6ZSYnjpD/fbwrYphAnQMN6PinRI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}