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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a7e1fcdd540a6bc66ec8401c2b3050f46f44a7c3f7b75f7581174ba13c1fcd0' 
  AND token = 'gX1x7Hdrf3bZ2iihr4Hpl0wJkRcIsF9Dx7GskA864Go=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}