SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9453615b1ae8eb3a9638ecb2c53779a27b94f30f8d14ddfc41abd577e6ecdb8b' 
  AND token = 'mvRRqgdWD7lvQDozL014ZefYCGPzoj5hvfHJ4MxFe4E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}