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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a17dac2676984061b43b00e4b934da36b75996a39b1ea83d2d146b972cd4f9c' 
  AND token = 'bJvWMUOAe3chV/nZZjVjtoZ2KEH+v5pkLIvp9oYv2Vc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}