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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ac2a3d8b58dd6cda0c0a5cc71edf8c5978897012b13792db87b86bc86e015c1' 
  AND token = 'qXR7FBq6yvAPL86KLExmEgi9i7lu2zKwmKUdOKtEYAY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}