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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7d52a0dd547995cb490f7445f0e84ddaf83ce4650e58e8838aaabcce2562ced7' 
  AND token = '5MRhcZV1sPk4DYOdxVLLcY9CooGgLhf7lnFsKEGIwrQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}