SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9cfe22fb9df8b3221f28ac500a0b5417907168df5d176e75c558ea1f02b94336' 
  AND token = 'xNkb57RRaz2awrcVEyiq0tbNW4XXUm5iGQl3lrxcIys=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}