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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eff35a7b024c28b506f32d83dd2975c52154095cf79516fffb13436668648f6a' 
  AND token = 'X8VQ4O6RsMxjivube3L1FMO8IJTSvwxwj4MB1rVmpQ0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}