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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0d104ad8f002497cc87116a4d71a0150913b7aacd4abff62482a8b24866bca04' 
  AND token = 'dfo1vtNGhDt/OyTTNPoGrJho6ES4XOnXmNokKKMctDI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}