SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef0eeb788bcf5f3afef1369cba13b54a88133f925c54429249320d947eb39a33' 
  AND token = 'wT6iqoWm7QYnrHqP95VqAm57EA6wPxpVoDi+7RTZbQ0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}