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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d7e4f2432d034b05e520ce90bcd331df0ef6c12f48e2bf530c6797db237d6b8' 
  AND token = 'M3dbZC+j6NtPMm2tlpozfYtT+vxlti6x0aa91NrZp1s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}