SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a6aa596d128710e2f4bfe68194a7c5026f0e1ba40e3e2b00fa8112fed0e0252' 
  AND token = 'vWCBV/Tfsdw4qyO2NIRCCFifmkAyvvjaThAdisJgL9U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}