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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f6c9a01f8bcc3034f7033d2bd1c3e7680a18f598c8baa43bb12f063637290482' 
  AND token = 'r2E2xZL5QuiP47qMbik/xbp9vN8hnswQQk+BrXdFuXY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}