SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7f818eec78ec838c90632360a98230a0f29b8d4482341f70117967eee503be4d' 
  AND token = 'll+NX8yeT4GQoVHncYZsySBzG0XHjUQlR3g65Ypw89s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}