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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '44f2f7da2537675039f57b9b3cb0c3daccbe31d7aa14341049ece9d47731a0ef' 
  AND token = 'GkTf7YlMj6DFu3rWqSJe2PP6HGLAypMB/85T0AUPNV8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00013

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}