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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '67c18da166c85d6fe86cf1b61e769dbb4f717534b73d8d7c9868b475e6cc0427' 
  AND token = '+Y4+oTST9Ze8iWv8GGViVBe9ciB0bS73kv5ApZt/z8w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}