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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '82ea0a45edf0d0e172bb179e262b1cc46986fde5b6ef62bcd298dac1c14a1bfc' 
  AND token = 'NSguqb7aDpMY+IlgJCJ4ow+mLkJBLpAtwiYSmhujRDQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}