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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a7ac4829f712a54a2c0e2ca3b185ace61afd1117a0a3a72b9c33d7d6e6f1f62d' 
  AND token = 'Rnku3pOn1FJE0sznIIqpK5GHq5Byru16lthYF04nrxM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}